Like I said k-lite installs a lot of junk which you don't need. And the more you install the more likely they will conflict with each other or something else on your system.
CCCP has the minimal you need to watch anime and it plays everything. *.mkv *.mp4 *.avi *.flv *.ts etc
K-lite installs everything with default settings, whcih are not the best settings. By default H264 only uses one core for example.
With CCCP everything has been customized for the best settings and with extensive testing.
So you will get the best performance with CCCP.
A new version of CCCP come out yesterday so give that a shot.

My encodes are guaranteed to work with CCCP but not with k-lite.
Oh yeah and if you continue to have have problems with subtitles click on autoload vsfilter when intstalling CCCP and see if that works.